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Message: <blockquote data-quote="Davy Crockett" data-source="post: 93874" data-attributes="member: 367">Speaking of 60s and woodstock reminded me why we are having this discussion.  The big thing back then was Angel Dust.  And rightfully so, everybody was scared of that crap and the reason Nixon made weed schedule one.   Angel Dust made people freak out and jump out of windows and the such,  They mixed it with with weed and smoked it.     If I can remember this,  Surely some of you older guys can,  It was on the evening news quite often during the Woodstock and the  Patty Hearst, Helter skelter era.      Phencyclidine (PCP), also known as angel dust and Sernyl among others,[SUP]<a href="https://en.wikipedia.org/wiki/Phencyclidine#cite_note-3" target="_blank">[3]</a>[/SUP] is a <a href="https://en.wikipedia.org/wiki/Dissociative_drug" target="_blank">dissociative drug</a>. PCP was brought to market in the 1950s as an <a href="https://en.wikipedia.org/wiki/Anesthesia" target="_blank">anesthetic</a> <a href="https://en.wikipedia.org/wiki/Pharmaceutical_drug" target="_blank">pharmaceutical drug</a> but was taken off the market in 1965 due to the high prevalence of <a href="https://en.wikipedia.org/wiki/Dissociative" target="_blank">dissociative</a><a href="https://en.wikipedia.org/wiki/Hallucinogen" target="_blank">hallucinogenic</a> side effects. Likewise, <a href="https://en.wikipedia.org/wiki/Ketamine" target="_blank">ketamine</a> was discovered by <a href="https://en.wikipedia.org/wiki/Parke-Davis" target="_blank">Parke-Davis</a> researchers as a better-tolerated derivative for use as an anesthetic <a href="https://en.wikipedia.org/wiki/Pharmaceutical_drug" target="_blank">pharmaceutical drug</a>. Since this time a number of synthetic derivatives of PCP have been sold as dissociative drugs for recreational and non-medical use.[SUP]<a href="https://en.wikipedia.org/wiki/Phencyclidine#cite_note-Morris-4" target="_blank">[4]</a>[/SUP]In <a href="https://en.wikipedia.org/wiki/Chemistry" target="_blank">chemical</a> structure, PCP is a member of the <a href="https://en.wikipedia.org/wiki/Arylcyclohexylamine" target="_blank">arylcyclohexylamine</a> <a href="https://en.wikipedia.org/wiki/Chemical_classification" target="_blank">class</a>, and, in <a href="https://en.wikipedia.org/wiki/Pharmacology" target="_blank">pharmacology</a>, it is a member of the family of<a href="https://en.wikipedia.org/wiki/Dissociative_anesthetic" target="_blank">dissociative anesthetics</a>. PCP works primarily as an <a href="https://en.wikipedia.org/wiki/NMDA_receptor_antagonist" target="_blank">NMDA receptor antagonist</a>, where it blocks the activity of the <a href="https://en.wikipedia.org/wiki/NMDA_receptor" target="_blank">NMDA receptor</a>. As an <a href="https://en.wikipedia.org/wiki/Addictive_drug" target="_blank">addictive drug</a>, PCP is associated with compulsive abuse.[SUP]<a href="https://en.wikipedia.org/wiki/Phencyclidine#cite_note-NHM-PCP_and_ketamine-1" target="_blank">[1]</a>[/SUP][SUP]<a href="https://en.wikipedia.org/wiki/Phencyclidine#cite_note-Morris-4" target="_blank">[4]</a>[/SUP][SUP]<a href="https://en.wikipedia.org/wiki/Phencyclidine#cite_note-5" target="_blank">[5]</a>[/SUP][SUP]<a href="https://en.wikipedia.org/wiki/Phencyclidine#cite_note-6" target="_blank">[6]</a>[/SUP]As a recreational drug, PCP may be ingested <a href="https://en.wikipedia.org/wiki/Oral_administration" target="_blank">orally</a>, <a href="https://en.wikipedia.org/wiki/Smoking" target="_blank">smoked</a>, <a href="https://en.wikipedia.org/wiki/Insufflation_(medicine)" target="_blank">insufflated</a> or <a href="https://en.wikipedia.org/wiki/Injection_(medicine)" target="_blank">injected</a>.[SUP]<a href="https://en.wikipedia.org/wiki/Phencyclidine#cite_note-InfoFacts-7" target="_blank">[7]</a>[/SUP]</blockquote>

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