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Message: <blockquote data-quote="BrockW" data-source="post: 441536" data-attributes="member: 5910"><p>They can. But disease pathogenesis studies have shown that positive animals accumulate prions in their retropharyngeal lymph nodes sooner, just after a month post infection (35-45 days). Whereas prions aren’t shown to be excreted in saliva until 3-9 months after infection, most 6+ months PI. Saliva also presents some other challenges for testing protocols. For instance, IHC uses a cross section of a LN and pathologist actually has to confirm staining in the right cells within the anatomy of the LN for it to be positive. Obviously, can’t take a cross section of saliva and it has no anatomy. Also, lymph nodes cant really be cross contaminated, but saliva could get cross contaminated when hunters submit heads.</p></blockquote><p></p>

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