Once, years ago when i was young, i hunted with a model 88 Winchester 243. Thought i needed speed so used, if i remember right, 87 grains factory.
Hit running whitetail at about 75 yards in front shoulder and that is where the bullet stay and no deeper. Shoulder bone was blown up, kept running and finally brother put down with 300.
Loved my 264 model 70 and with that rifle i did hit a running mule deer in shoulder at about 75 yards. 140 grain factory Winchester shell. Blew shoulder up and that was all. Deer kept running and son put down with 7mm.
Imho to much speed or to little grains (maybe get a different kind of bullet for the speed).
Shoot what one believes in but i will never used that 264 again (now have 11 full boxes of shells with a $12 ticket price) or if i had a 243 model 88 yet for deer, if i ever get a license again will use my 300 Weatherby made in 1959 (and i fully believe in that rifle).
However i continue to dream of shooting that large buck with my model 92 in 25-20. But it is a dream and that model 92 makes me feel real good when i carry but i realize it isn't going to ever happen, to little gun even if it did take down the Jordan buck.
As i said, just believe in what you carry and it will go well but it does not hurt to carry a little insurance to help with that feeling when the bullet does not go where it was meant to go. db
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And i do have more than enough shells for my Weatherby from the 1960's to last me a life time (if i ever get a license again). Price tag on box of $7.70. (i did practice with some new shells but did use those old shells on the last two mule deer, old but did work, one at 100 yards and one at 220 yards, both one shot, clean through, dad would be proud of that gun if he could watch from up above as he was with that rifle when he hunted with it) db